|Speaker||Prof. Joohoon Kim|
|Date||Thu. 12 Oct. 2017|
|Venue||#331, Asan Hall, College of Science|
“Versatile Dendrimer-Encapsulated Nanoparticles for Analytical Applications”
There are two main topics presented here. The first topic is the synthesis of dendrimer-encapsulated nanoparticles (DENs) and their useful properties for analytical applications. Specifically, we synthesized Pt DENs containing an average of 55 Pt atoms using amine-terminated 4th-generation polyamidoamine (PAMAM) dendrimers, which we denote as G4-NH2(Pt55). The synthesized G4-NH2(Pt55) exhibited peroxidase-mimetic activity, superior or at least comparable to that of natural peroxidase enzymes such as horse radish peroxidase (HRP), and thus could be utilized as peroxidase-mimetic labels for sensitive colorimetric assays. In addition, we synthesized Pt DENs using amine-terminated nth generation PAMAM (Gn-NH2, n = 6 and 4) dendrimers. The synthesized Pt DENs showed different sizes over the range of 1-3 nm, but were fairly uniform and monodispersed in size with subnanometer accuracy. Interestingly, we found the size-dependent catalytic activity of the Pt DENs having well-defined sizes with subnanometer accuracy for the enhanced chemiluminescence of the luminol/H2O2 system. We demonstrated the analytical versatility of the Pt DEN-catalyzed generation of chemiluminescence in oxidase-based analyses toward various oxidase substrates including choline, glucose, and cholesterol. The second topic is the functionalization of chip surfaces with DENs for fabrication of versatile chip-based analytical platforms. Two types of surface decoration methods will be mainly discussed: electrochemical decoration of glassy carbon and indium tin oxide surfaces, and covalent decoration of chemically converted graphene (CCG) surfaces. A brief description will be also presented how the chip-based analytical platforms can be applied as electrochemical, optical, and electrochemiluminescence (ECL) sensor chips based on the various transduction techniques.
1. Kwon, J.; Park, S. K.; Lee, Y.; Lee, J. S.*; Kim, J.* Biosens. Bioelectron., 2017, 87, 89-95.
2. Lim, H.; Ju, Y.; Kim, J.* Anal. Chem., 2016, 88, 4751-4758.
3. Ju Y.; Kim, J.* Chem. Commun., 2015, 51, 13752-13755.
4. Kim, Y.; Kim, J.* Anal. Chem., 2014, 86, 1654-1660.
5. Kim, J. M.; Kim, J.*, Song, J. K.* et al. ChemPhysChem, 2014, 15, 2917-2921.
6. Yoon, J.; Kim, H.-S.*, Kim, J.* et al. Chem. Commun., 2014, 50, 7670-7672.
7. Lee, S. B.; Ju, Y.; Kim, Y.; Koo, C. M.; Kim, J.* Chem. Commun., 2013, 49, 8913-8915.
8. Kim, J. M.; Kim, J.; Kim, J.* Chem. Commun., 2012, 48, 9233-9235.
9. Ju, H.; Koo, C. M.; Kim, J.* Chem. Commun., 2011, 47, 12322-12324.
10. Kim, T. H.; Choi, H. S.; Go, B. R.; Kim, J.* Electrochem. Commun., 2010, 12, 788-791.
Prof. Joohoon Kim
Department of Chemistry, Kyung Hee University, Korea
|Notice||Fall semester 2017 Seminar Schedule||-||-|
|48||[January 24, 2018] Electro-Optic Organic THz Wave Sources||Prof. O-Pil Kwon(Ajou University)||January 24, 2018 (Wednesday)|
|47||[Thu. 30 Nov. 2017] Prof. Sunmin Ryu/Department of Chemistry, POSTECH, Pohang, South Korea||Prof. Sunmin Ryu||Thu. 30 Nov. 2017|
|46||[Thu. 23 Nov. 2017] Prof. Sung-Gon Kim/Department of Chemistry, Kyonggi University, Suwon, Korea||Prof. Sung-Gon Kim||Thu. 23 Nov. 2017|
|45||[November 14, 2017] Zero-Point Energy, Fluctuations, and Dissipation : A (Mostly) Quantum-Optical Perspective||Prof. Milonni, Peter||November 14, 2017|
|44||[Thu. 16 Nov. 2017] Prof. Hyungjun Kim/Department of Chemistry, and Graduate school of Energy, Environment, Water, and Sustainability (EEWS), KAIST, Daejeon, Korea||Prof. Hyungjun Kim||Thu. 16 Nov. 2017|
|43||[Fri. 30 Oct. 2017] Prof. Igor Rodin/Department of Chemistry, Moscow State University, Moscow, Russia||Prof. Igor Rodin||Fri. 30 Oct. 201|
|42||[October 31, 2017] New ways of vision: Protein structures in translational medicine and business development, my experience||Prof. Robert Huber(1988 Nobel Prize in Chemistry)||October 31, 2017|
|41||[Thu. 26 Oct. 2017] Dr. Jung-Nyoung Heo/Center for Medicinal Chemistry Research, Korea Research Institute of Chemical Technology, Daejeon, Korea||Dr. Jung-Nyoung Heo||Thu. 26 Oct. 2017|
|40||[October 25, 2017] Ultrafast electron microscopy: applications in chemical and materials sciences||Dr. Byung-Kuk Yoo||October 25, 2017|
|39||[Mon. 16 Oct. 2017] Prof. Kirk S. Schanze/Department of Chemistry, University of Texas at San Antonio, Texas, USA||Prof. Kirk S. Schanze||Mon. 16 Oct. 2017|
|38||[Fri. 13 Oct. 2017] Dr. J. Nathan Hohman/The Molecular Foundry, Lawrence Berkeley National Laboratory, California, USA||Dr. J. Nathan Hohman||Fri. 13 Oct. 2017|
|»||[Thu. 12 Oct. 2017] Student Host Colloquium : Versatile Dendrimer-Encapsulated Nanoparticles for Analytical Applications||Prof. Joohoon Kim||Thu. 12 Oct. 2017|
|36||[October 10, 2017] Novel Terahertz Spectroscopies||Director Mischa Bonn||Tue, October 10, 2017|
|35||[Thu. 28 Sep. 2017] Prof. Eunsung Lee/Department of Chemistry, POSTECH and Center for Self–assembly and Complexity, Institute for Basic Science (IBS), Pohang, Republic of Korea||Prof. Eunsung Lee||Thu. 28 Sep. 2017|
|34||[Thu. 14 Sep. 2017] Prof. Dokyoung Kim/Department of Anatomy and Neurobiology, Kyung Hee University, Seoul||Prof. Dokyoung Kim||Thu. 14 Sep. 2017|
|33||7th Jilin-Korea-Waseda Alliance Annual Symposium||-||August 17 ~ 19, 2017|
|32||[Wed. 5 July. 2017] Seminar is canceled!||-||-|
|31||[Fri. 16 Jun. 2017] Prof. Martin Thuo/Department of Materials Science and Engineering, Iowa State University, USA||Prof. Martin Thuo||Fri. 16 Jun. 2017|
|30||[Thu. 8 Jun. 2017] Prof. Won-jin Chung/Department of Chemistry, GIST, Gwangju, Republic of Korea||Prof. Won-jin Chung||Thu. 8 Jun. 2017|
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