Loading...
2019.07.02 10:43

[July 11. 2019] Coordination Chemistry in 19F Magnetic Resonance Imaging: Agents for Illuminating Biological Environments in Vitro and in Vivo

Atachment
Attachment '1'
?

Shortcut

PrevPrev Article

NextNext Article

+ - Up Down Comment Print
?

Shortcut

PrevPrev Article

NextNext Article

+ - Up Down Comment Print
Extra Form
Speaker Prof. Emily Que(The University of Texas at Austin)
Date Thu. 11 July. 2019
Time 4:30pm
Venue #331, Asan Hall, College of Science

Coordination Chemistry in 19F Magnetic Resonance Imaging: Agents for Illuminating

Biological Environments in Vitro and in Vivo

 

19F Magnetic resonance imaging (MRI) is an emerging technique for in vivo imaging, showing great promise due to the favorable NMR properties of the fluorine nucleus (high sensitivity, large ppm range) and the lack of detectable fluorine signal in biological systems. Imaging agents can be designed that exhibit either a turn-on or chemical shift response that is selective for a specific biological molecule or event. We are developing a series of metal complexes designed to report on different biological environments associated reductive stress (hypoxia), oxidative stress, changes in pH, metal ion concentration, and enzymatic activity. These sensors act via a switch from a paramagnetic to diamagnetic state upon reduction or oxidation at the metal center. Through careful tuning of the ligand scaffold, we have developed selective sensors for hypoxia and oxidative stress, showing promise for future applications for in vivo detection of these states in both cellular and animal disease models. New enhanced nanoparticle-based platforms based on metal-doped perfluorocarbons will also be discussed.

 

20190711_대학원특별세미나_Emily Que.pdf


  1. Fall semester 2016 Seminar Schedule

    -
    -
    Read More
  2. Spring semester 2017 Seminar Schedule

    -
    -
    Read More
  3. [Thu. 27 Apr. 2017] Seminar was canceled!

    -
    -
    Read More
  4. [Wed. 5 July. 2017] Seminar is canceled!

    -
    -
    Read More
  5. Fall semester 2017 Seminar Schedule

    -
    -
    Read More
  6. Fall semester 2018 Seminar Schedule

    -
    -
    Read More
  7. Spring semester 2019 Seminar Schedule

    -
    -
    Read More
  8. Announcements Graduate Seminar Spring Semester 2021

    .
    .
    Read More
  9. Announcement for Graduate Seminar Class, Fall Semester 2020

    Announcement for Graduate Seminar Class, Fall Semester 2020
    Announcement for Graduate Seminar Class, Fall Semester 2020
    Read More
  10. 2023 Germany-Korea On-Site Plenary Discussion on Computational Electrochemistry

    BK21 Chemistry Education Research Center
    April 17, 2023 (Mon)
    Read More
  11. April 21, 2023 (Fri) Professor Bangsun Dong

    Professor Bangsun Dong (Sogang University Department of Chemistry)
    April 21, 2023 (Fri)
    Read More
  12. April 29 (Fri) Graduate Seminar / Luther Beegle, PhD

    Luther Beegle, PhD (Principle Investigator of Perseverance Rover SHEROLC instrument, Mars 2020 mission NASA-Jet Propulsion Laboratory, California Institute of Technology)
    April 29, 2022 (Fri)
    Read More
  13. 7th Jilin-Korea-Waseda Alliance Annual Symposium

    -
    August 17 ~ 19, 2017
    Read More
  14. June 10th (Fri) Graduate Seminar / Bing Zhang, Ph.D.

    Bing Zhang, Ph.D. (Baylor College of Medicine)
    Fri, Jun 10, 2022
    Read More
  15. [Fri. 13 Oct. 2017] Dr. J. Nathan Hohman/The Molecular Foundry, Lawrence Berkeley National Laboratory, California, USA

    Dr. J. Nathan Hohman
    Fri. 13 Oct. 2017
    Read More
  16. [Fri. 16 Jun. 2017] Prof. Martin Thuo/Department of Materials Science and Engineering, Iowa State University, USA

    Prof. Martin Thuo
    Fri. 16 Jun. 2017
    Read More
  17. [Fri. 17 Mar. 2017] 9th RINS Symposium

    -
    Fri. 17 Mar. 2017
    Read More
  18. [Fri. 30 Oct. 2017] Prof. Igor Rodin/Department of Chemistry, Moscow State University, Moscow, Russia

    Prof. Igor Rodin
    Fri. 30 Oct. 201
    Read More
  19. [Fri. 17 Jun. 2016] Prof. Jianwei Sun/Remote Control in Brønsted Acid Catalysis: New Strategies for the Synthesis of Chiral Building Blocks and Medium Rings

    Prof. Jianwei Sun
    Friday 17 June 2016
    Read More
  20. February 24 (Fri) Lawrence Yoon Suk Lee

    Lawrence Yoon Suk Lee (Hong Kong Polytechnic University)
    Friday, February 24, 2023
    Read More
Board Pagination ‹ Prev 1 2 3 4 5 6 7 8 Next ›
/ 8

Designed by sketchbooks.co.kr / sketchbook5 board skin

나눔글꼴 설치 안내


이 PC에는 나눔글꼴이 설치되어 있지 않습니다.

이 사이트를 나눔글꼴로 보기 위해서는
나눔글꼴을 설치해야 합니다.

설치 Cancel

Sketchbook5, 스케치북5

Sketchbook5, 스케치북5

Sketchbook5, 스케치북5

Sketchbook5, 스케치북5

Department of Chemistry, Korea University, Tel) +82-2-3290-3120
145 Anam-ro Seongbuk-gu Seoul, 02841, Republic of Korea
Copyright(c) 2014 KOREA UNIVERSITY DEPARTMENT of CHEMISTRY. All right reserved.