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2016.10.17 10:24

[Thu. 20 Oct. 2016] Prof. Chan Hyuk Kim/Novel Small Molecule-based Approaches for Cancer Immunotherapy

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Speaker Prof. Chan Hyuk Kim
Date Thursday 20 October 2016
Time 5:00pm
Venue #331, Asan Hall, College of Science

“Novel Small Molecule-based Approaches for Cancer Immunotherapy”

 

Cancer immunotherapy has been drawing growing attention as a novel promising therapeutic modality for cancer. Unlike conventional chemo- or radiotherapy, immunotherapy treats cancer by unleashing the suppressed activity of the patient’s own immune system and harnessing its power to fight cancer, to achieve robust anti-tumor responses while minimizing collateral damages to normal tissues. In particular, T cell-based immunotherapeutics such as bispecific antibodies and chimeric antigen receptor (CAR) T cells have generated unprecedented responses in clinics, and have become promising therapeutic modalities for the treatment of refractory cancers. Despite their success, however, there are several issues, such as unfavorable pharmacokinetics and biophysical properties as well as safety-related issues, associated with these biological drugs, preventing more widespread and safe application of these promising therapeutics. In this talk, I will discuss our recent efforts on addressing these issues by using synthetic small molecule ligands and biorthogonal conjugation chemistry to generate next-generation cancer immunotherapeutics.

 

Prof. Chan Hyuk Kim

Department of Chemistry, Boston College, Massachusetts, USA


List of Articles
No. Subject Speaker Date
Notice Spring semester 2017 Seminar Schedule file - -
13 [Thu. 3 Nov. 2016] Prof. Min-Sik Kim/Mass spectrometry and its applications to Biological Discovery Prof. Min-Sik Kim Thursday 3 November 2016
» [Thu. 20 Oct. 2016] Prof. Chan Hyuk Kim/Novel Small Molecule-based Approaches for Cancer Immunotherapy Prof. Chan Hyuk Kim Thursday 20 October 2016
11 [Mon. 13 Oct. 2016] Prof. Amir H. Hoveyda/Multicomponent Catalytic Synthesis of Organoboron Compounds for Scalable Natural Product Synthesis Prof. Amir H. Hoveyda Monday 13 October 2016
10 [Thu. 6 Oct. 2016] Prof. Young S. Park/Atomistic Molecular Engineering of Polycyclic Aromatic Hydrocarbons Prof. Young S. Park Thursday 6 October 2016
9 [Thu. 29 Sep. 2016] Prof. Tae-Young Yoon/Observation of Single Membrane Proteins under Mechanical Tension Prof. Tae-Young Yoon Thursday 29 September 2016
8 [Thu. 22 Sep. 2016] Prof. Anna Lee/Organocatalyzed Asymmetric Reactions Prof. Anna Lee Thursday 22 September 2016
7 [Thu. 8 Sep. 2016] Prof. Jaeyoung Sung/Stochastic chemical dynamics in living cells and its consequence for the control capacity of living cells over biological functions Prof. Jaeyoung Sung Thursday 8 September 2016
6 Fall semester 2016 Seminar Schedule file - -
5 [Fri. 17 Jun. 2016] Prof. Jianwei Sun/Remote Control in Brønsted Acid Catalysis: New Strategies for the Synthesis of Chiral Building Blocks and Medium Rings Prof. Jianwei Sun Friday 17 June 2016
4 [Thu. 9 Jun. 2016] Prof. Yong-Young Noh/Development of Printed Large Area Organic Transistors and Integrated Circuits Prof. Yong-Young Noh Thursday 9 June 2016
3 [Thu. 2 Jun. 2016] Prof. Sunkyu Han/Total Syntheses of Complex Alkaloids Inspired by Biosynthetic Hypotheses Prof. Sunkyu Han Thursday 2 June 2016
2 [Thu. 26 Jun. 2016] Prof. Sung June Cho/Structural Elucidation of Novel Zeolite by Dual Space Approaches Using X-ray Powder Diffraction Prof. Sung June Cho Thursday 26 May 2016
1 [Thu. 19 May. 2016] Prof. Zhuang Liu/Nanotechnology for enhanced cancer radiation therapy and immunotherapy Prof. Zhuang Liu Thursday 19 May 2016
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