Recent Progress in the Chemistry of Pyridazinones for Functional Group Transformations

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author Hyo Jae Yoon
journal J. Org. Chem. (JOCSynopsis) (DOI: 10.1021/acs.joc.7b02481)


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While N-hetereocycles have received significant attention in organic synthesis and other research fields, the chemistry of pyridazine, six-membered aromatic ring with adjacent two nitrogen atoms, and its derivatives has been relatively little understood. This Synopsis describes recent progress made in the synthesis of pyridazine derivatives—particularly, pyridazin-3(2H)-ones—and their utility as efficient and recyclable functional group carriers (FGCs) for various important organic reactions.




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